Compound ID | 3206
BN-1
Synonym(s): BN1 | BN 1
Class: Natural product antibiotic
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Active against Staphylococcus aureus, Streptococcus faecalis, Streptococcus pyogenes, Streptococcus pneumoniae, Corynebacterium diphtheriae, Neisseria gonorrhoeae (only Gram-negative it is active against), Mycobacterium tuberculosis |
| Description: | Natural product from Micromonospora verruculosa MCRL 0404; part of the M-92 antibiotic complex; protects mice from Staphylococcus aureus infection when administered intraperitoneally; shows cytotoxicity towards HeLa-S3 cells at 4 mg/L (MIC at 0.00625 mg/L) |
| Institute where first reported: | Microbiological Research Laboratory, Tanabe Seiyaku Co., Ltd. |
| Year first mentioned: | 1982 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.jstage.jst.go.jp/article/antibiotics1968/35/11/35_11_1441/_article/-char/en |
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