Compound ID | 3207

Update compound information

Diazaquinomycin A

Synonym(s): OM-704 A

Class: Natural product antibiotic

Agent Type: Natural product; Small molecule; Direct acting;
Spectrum of activity: Gram-positive
Mechanism of action: Folate synthesis inhibitor
Target Pathogen: Active against Staphylococcus aureus (including penicillin- and erythromycin-resistant strains) and Streptococcus faecium
Description: Natural product from Streptomyces sp.
Year first mentioned: 1982
Development status: Experimental
Chemical structure(s):
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Molecular weight: 354.4
Iso. SMILES: CCCC1=C(C(=O)NC2=C1C(=O)C3=C(C2=O)NC(=O)C(=C3CCC)C)C
InChI Key: WZZGVUSWZMBPPL-UHFFFAOYSA-N
Can. SMILES: CCCC1=C(C)C(=O)NC2=C1C(=O)C3=C(C2=O)NC(=O)C(=C3CCC)C
InChI: InChI=1S/C20H22N2O4/c1-5-7-11-9(3)19(25)21-15-13(11)17(23)14-12(8-6-2)10(4)20(26)22-16(14)18(15)24/h5-8H2,1-4H3,(H,21,25)(H,22,26)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/122105
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/38/8/38_8_1025/_article/-char/en
  • https://www.jstage.jst.go.jp/article/antibiotics1968/35/11/35_11_1425/_article/-char/en

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