Compound ID | 3214

Update compound information

Clerocidin

Synonym(s): PR-1350

Class: Natural product antibiotic

Agent Type: Natural product; Small molecule; Direct acting;
Spectrum of activity: Gram-positive, Gram-negative & Antimycobacterial
Mechanism of action: Alkylates DNA
Target Pathogen: Active against Staphylococcus aureus, Streptococcus pyogenes, Streptococcus faecalis, Neisseria sp., Escherichia coli, Klebsiella pneumoniae, and Mycobacterium phlei
Description: Natural product from Oidiodendron truncatum
Institute where first reported: Leo Pharmaceutical Products
Year first mentioned: 1983
Development status: Experimental
Chemical structure(s):
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Molecular weight: 696.87
Iso. SMILES: CC1CCC2(C(C1(C)CC3C4(CO4)C5(C(O3)OC6(C(O5)OC(C67CO7)CC8(C(CCC9(C8CCC=C9C=O)C)C)C)O)O)CCC=C2C=O)C
InChI Key: LKJYEAJRWPUOGW-UHFFFAOYSA-N
Can. SMILES: CC1CCC2(C)C(=CCCC2C1(C)CC3C4(CO4)C5(C(O3)OC6(C(OC(CC7(C)C(C)CCC8(C)C(=CCCC87)C=O)C96CO9)O5)O)O)C=O
InChI: InChI=1S/C40H56O10/c1-23-13-15-33(3)25(19-41)9-7-11-27(33)35(23,5)17-29-37(21-45-37)39(43)31(47-29)49-40(44)32(50-39)48-30(38(40)22-46-38)18-36(6)24(2)14-16-34(4)26(20-42)10-8-12-28(34)36/h9-10,19-20,23-24,27-32,43-44H,7-8,11-18,21-22H2,1-6H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/9896400
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/46/3/46_3_526/_article
  • https://www.jstage.jst.go.jp/article/antibiotics1968/36/7/36_7_753/_article/-char/en

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