Compound ID | 3221

Update compound information

Clavalanine

Synonym(s): Ro 22-5417  |  Ro 225417  |  Ro 225417

Class: Natural product antibiotic

Spectrum of activity: Gram-positive
Details of activity: Intervenes with methionine synthesis
Description: Natural product from Streptomyces clavuligerus ; contains beta-lactam scaffold
Institute where first reported: Chemical Research Department, Hoffmann-La Roche Inc.
Year first mentioned: 1983
Development status: Experimental
Chemical structure(s):
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Molecular weight: 200.19
Iso. SMILES: C1[C@H]2N(C1=O)C[C@@H](O2)C[C@@H](C(=O)O)N
InChI Key: KCAIYJDHLVYANU-VPLCAKHXSA-N
Can. SMILES: C([C@H]1CN2C(=O)C[C@@H]2O1)[C@@H](C(=O)O)N
InChI: InChI=1S/C8H12N2O4/c9-5(8(12)13)1-4-3-10-6(11)2-7(10)14-4/h4-5,7H,1-3,9H2,(H,12,13)/t4-,5-,7-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/194618
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/36/3/36_3_217/_article
  • https://pubs.acs.org/doi/10.1021/jo00219a008
  • https://www.jstage.jst.go.jp/article/antibiotics1968/36/3/36_3_208/_article

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