Compound ID | 3233
ε-Poly-L-lysine
Class: Antimicrobial peptide
| Agent Type: | Natural product; Small molecule; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Membrane-active agent |
| Target Pathogen: | Active against Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris, and Staphylococcus aureus |
| Description: | Natural product from Streptomyces albukus; homopolymer (25~30 𝛆-PL); shows anti-phage activity; antibiotic activity is proportional to increasing number of size of polymer with greatest activity showing at n=25~30 (Escherichia coli MIC at 1 mg/L) |
| Year first mentioned: | 1984 |
| Development status: | Experimental |
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