Compound ID | 3233

ε-Poly-L-lysine

Class: Antimicrobial peptide

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris, and Staphylococcus aureus; membrane-active agent
Description: Natural product from Streptomyces albukus; homopolymer (25~30 𝛆-PL); shows anti-phage activity; antibiotic activity is proportional to increasing number of size of polymer with greatest activity showing at n=25~30 (Escherichia coli MIC at 1 mg/L)
Year first mentioned: 1984
Development status: Experimental

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