Compound ID | 3238

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Lavendomycin

Class: Antimicrobial peptide

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus aureus and Streptococcus faecalis
Description: Natural product from Streptomyces lavendulae subsp. brasilicus; protects mice from Staphylococcus sp. and Streptococcus sp. when administered subcutaneously 13.2 mg/kg (acute toxicity seen at 2 g/kg)
Institute where first reported: Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.
Year first mentioned: 1985
Development status: Experimental
Chemical structure(s):
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Molecular weight: 666.77
Iso. SMILES: C/C=C(/C(=O)N[C@@H](CO)C(=O)O)\NC(=O)[C@@H]1CCCN1C(=O)[C@@H]2CCCCN2C(=O)[C@H]([C@@H](C)N)NC(=O)[C@H]([C@H](C)CCN=C(N)N)N
InChI Key: ZLIFOKMGWXMKQW-BDKIHTTOSA-N
Can. SMILES: C/C=C(/C(=O)N[C@@H](CO)C(=O)O)\NC(=O)[C@@H]1CCCN1C(=O)[C@@H]2CCCCN2C(=O)[C@H]([C@@H](C)N)NC(=O)[C@H]([C@H](C)CCN=C(N)N)N
InChI: InChI=1S/C29H50N10O8/c1-4-17(23(41)36-18(14-40)28(46)47)35-24(42)19-9-7-13-38(19)26(44)20-8-5-6-12-39(20)27(45)22(16(3)30)37-25(43)21(31)15(2)10-11-34-29(32)33/h4,15-16,18-22,40H,5-14,30-31H2,1-3H3,(H,35,42)(H,36,41)(H,37,43)(H,46,47)(H4,32,33,34)/b17-4-/t15-,16-,18+,19+,20+,21+,22+/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/14683533
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968/38/6/38_6_691/_article/-char/en

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