Compound ID | 3239

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Nourseimycin

Synonym(s): Alahopcin

Class: Antimicrobial peptide

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus aureus; likely cell wall synthesis inhibitor
Description: Natural product from Streptomyces albulus subsp.ochragerus; protects mice infected with Staphylococcus aureus when administered subcutaneously at 27 mg/kg (acute toxicity seen at 1 g/kg)
Institute where first reported: Central Research Division, Takeda Chemical Ind., Ltd.
Year first mentioned: 1983
Development status: Experimental
Chemical structure(s):
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Molecular weight: 261.23
Iso. SMILES: CC(C(=O)NC(C(CC=O)C(=O)NO)C(=O)O)N
InChI Key: FCFXHAVNZIHNQN-UHFFFAOYSA-N
Can. SMILES: CC(C(=O)NC(C(CC=O)C(=O)NO)C(=O)O)N
InChI: InChI=1S/C9H15N3O6/c1-4(10)7(14)11-6(9(16)17)5(2-3-13)8(15)12-18/h3-6,18H,2,10H2,1H3,(H,11,14)(H,12,15)(H,16,17)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/10355275
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/38/3/38_3_302/_article/-char/en
  • https://www.jstage.jst.go.jp/article/antibiotics1968/38/3/38_3_285/_article/-char/en

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