Compound ID | 326
BMS-28232
Class: Beta-lactam (cephalosporin)
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | This is not hydrolysed by TEM-1 but is hydrolysed by new TEM and SHV enzymes |
| Institute where first reported: | Bristol Myers Research Institute, Ltd., Japan |
| Year first mentioned: | 1987 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| Reason Dropped: | Prodrug of this (BMY 28271) was generated so with better absorption from intestinal mucosa so this may have very low absorption, additionally it is hydrolysed by new β-lactamases |
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