Furaltadone

Synonym(s): nitrofurmethone  |  altafur  |  furazolin

Class: Nitrofuran

Spectrum of activity:	Gram-positive  &  Gram-negative
Details of activity:	Active against Staphylococcus aureus, Streptococcus sp., Enterococcus sp., Pneumococcus, Escherichia coli, and Klebsiella pneumoniae
Description:	Synthetic compound
Year first mentioned:	1959
Highest developmental phase:	Clinical trial in 1959-1960
Development status:	Inactive
Reason Dropped:	Lack of therapeutic effect in complicated infections

Chemical structure(s):
Canonical SMILES:	C1=C(/C=N/N2CC(CN3CCOCC3)OC2=O)OC(=C1)[N+](=O)[O-]
Isomeric SMILES:	C1COCCN1CC2CN(C(=O)O2)/N=C/C3=CC=C(O3)[N+](=O)[O-]
InChI:	InChI=1S/C13H16N4O6/c18-13-16(14-7-10-1-2-12(22-10)17(19)20)9-11(23-13)8-15-3-5-21-6-4-15/h1-2,7,11H,3-6,8-9H2/b14-7+
InChI Key:	YVQVOQKFMFRVGR-VGOFMYFVSA-N

External links:
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/9553856
Main Source:	https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/565983