Compound ID | 3275

Update compound information

Furaltadone

Synonym(s): nitrofurmethone  |  altafur  |  furazolin

Class: Nitrofuran

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus, Streptococcus sp., Enterococcus sp., Pneumococcus, Escherichia coli, and Klebsiella pneumoniae
Description: Synthetic compound
Year first mentioned: 1959
Highest developmental phase: Clinical trial in 1959-1960
Development status: Inactive
Reason Dropped: Lack of therapeutic effect in complicated infections
Chemical structure(s):
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Molecular weight: 324.29
Iso. SMILES: C1COCCN1CC2CN(C(=O)O2)/N=C/C3=CC=C(O3)[N+](=O)[O-]
InChI Key: YVQVOQKFMFRVGR-VGOFMYFVSA-N
Can. SMILES: C1=C(/C=N/N2CC(CN3CCOCC3)OC2=O)OC(=C1)[N+](=O)[O-]
InChI: InChI=1S/C13H16N4O6/c18-13-16(14-7-10-1-2-12(22-10)17(19)20)9-11(23-13)8-15-3-5-21-6-4-15/h1-2,7,11H,3-6,8-9H2/b14-7+
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/9553856
Citation: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/565983

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