3-Hydroxycezomycin

Synonym(s): AC7230  |  AC 7230  |  AC-7230

Class: Natural product antibiotic (ionophore; pyrroloether)

Spectrum of activity:	Gram-positive
Details of activity:	Active against Staphylococcus aureus, Streptococcus epidermidis, Streptococcus pyogenes, Enterococcus faecalis, and Corynebacterium diphtheriae
Description:	Natural product from Dactylosporangium sp. AC7230
Institute where first reported:	Toyo Jozo Co., Ltd.
Year first mentioned:	1987
Development status:	Experimental

Chemical structure(s):
Canonical SMILES:	C[C@@H]1CCC2([C@H](C)C[C@@H](C)[C@@H]([C@H](C)C(=O)C3=CC=CN3)O2)O[C@@H]1CC4=NC5=C(C(=CC=C5O4)O)C(=O)O
Isomeric SMILES:	C[C@@H]1CCC2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)C3=CC=CN3)C)C)O[C@@H]1CC4=NC5=C(O4)C=CC(=C5C(=O)O)O
InChI:	InChI=1S/C28H34N2O7/c1-14-9-10-28(16(3)12-15(2)26(37-28)17(4)25(32)18-6-5-11-29-18)36-21(14)13-22-30-24-20(35-22)8-7-19(31)23(24)27(33)34/h5-8,11,14-17,21,26,29,31H,9-10,12-13H2,1-4H3,(H,33,34)/t14-,15-,16-,17-,21-,26+,28?/m1/s1
InChI Key:	WULUUVLPLGXOFP-GHLNLJSUSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/128567

External links:
Main Source:	https://www.jstage.jst.go.jp/article/antibiotics1968/40/2/40_2_239/_article/-char/en