Compound ID | 3308

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Okilactomycin

Class: Natural product antibiotic

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, and Streptococcus pneumoniae; likely RNA synthesis inhibitor
Description: Natural product from Streptomyces griseoflavus subsp. zamamiensis; also shows anti-tumour activity
Institute where first reported: Yamanouchi Pharmaceutical Co., Ltd.
Year first mentioned: 1987
Development status: Experimental
Chemical structure(s):
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Molecular weight: 416.51
Iso. SMILES: C[C@@H]1CCC[C@H]2C=C([C@H](C[C@@]23[C@H]4[C@](C(=O)C(=C)[C@H](O4)[C@@H](C1)C)(C(=O)O3)C)C)C(=O)O
InChI Key: KQZIMLFKBWIOJJ-ZRHSTDQJSA-N
Can. SMILES: C[C@@H]1CCC[C@H]2C=C([C@@H](C)C[C@@]23[C@H]4[C@](C)(C(=O)C(=C)[C@@H]([C@H](C)C1)O4)C(=O)O3)C(=O)O
InChI: InChI=1S/C24H32O6/c1-12-7-6-8-16-10-17(20(26)27)14(3)11-24(16)21-23(5,22(28)30-24)19(25)15(4)18(29-21)13(2)9-12/h10,12-14,16,18,21H,4,6-9,11H2,1-3,5H3,(H,26,27)/t12-,13-,14+,16+,18-,21-,23+,24+/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/10477012
Citations:
  • https://www.nature.com/articles/ja20088
  • https://www.jstage.jst.go.jp/article/antibiotics1968/40/11/40_11_1475/_article

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