Compound ID | 3314

Update compound information

MF 5137

Synonym(s): 6-amino-1-cyclopropyl-8-methy-7-(5,6, 7 ,8-tetrahydroisoquinolinyl)-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid

Class: Quinolone

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Neisseria gonorrhoeae, Staphylococcus aureus, Groups A and B streptococci, Enterococcus faecalis, and Streptococcus pneumoniae; active against ciprofloxacin resistant strains
Description: Synthetic compound; 6-aminoquinolone; a quinolone which contains amino acid at position C-6 instead of fluorine atom
Institute where first reported: Mediolanum Farmaceutici
Year first mentioned: 1995
Development status: Experimental
Chemical structure(s):
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Molecular weight: 389.45
Iso. SMILES: CC1=C2C(=CC(=C1N3CCC4=CC=CC=C4C3)N)C(=O)C(=CN2C5CC5)C(=O)O
InChI Key: LLVLMYRWABCVEU-UHFFFAOYSA-N
Can. SMILES: CC1=C(C(=CC2=C1N(C=C(C2=O)C(=O)O)C3CC3)N)N4CCC5=C(C=CC=C5)C4
InChI: InChI=1S/C23H23N3O3/c1-13-20-17(22(27)18(23(28)29)12-26(20)16-6-7-16)10-19(24)21(13)25-9-8-14-4-2-3-5-15(14)11-25/h2-5,10,12,16H,6-9,11,24H2,1H3,(H,28,29)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/460150
Citation: https://link.springer.com/article/10.2165/00003495-199500492-00067

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