Compound ID | 3328
A42867
Class: Glycopeptide
| Spectrum of activity: | Gram-positive |
| Details of activity: | Active against aerobic and anaerobic Gram-positives; likely cell wall synthesis inhibitor |
| Description: | Natural product from Nocardia sp.; ristocetin-vancomycin type; shows an effective dose (ED50) of 1.54 gm/kg in Streptococcus pyogenes infected mice; inferior to teicoplanin in treating mice infected with Enterococcus faecalis or Clostridium difficile; similar to vancomycin and teicoplanin in treating mice infected with coagulase-negative Staphylococcus aureus |
| Institute where first reported: | Merrell Dow Research Institute, Lepetit Reseach Center |
| Year first mentioned: | 1989 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.jstage.jst.go.jp/article/antibiotics1968/42/4/42_4_497/_article/-char/en |
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