Compound ID | 3358

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SF2457 

Class: Nucleoside analogue

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus, Enterococcus faecium, Bacillus anthracis, Salmonella typhi, and Salmonella enteritidis; likely protein synthesis inhibitor
Description: Natural product from Nocardia brasiliensis; an aminohexopyranose nucleoside
Institute where first reported: Meiji Seika Kaisha, Ltd.
Year first mentioned: 1992
Development status: Experimental
Chemical structure(s):
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Molecular weight: 590.63
Iso. SMILES: CC1C(C(C(C(O1)OC2C(OC(CC2O)N3C=CC(=NC3=O)NC(=O)C4=CC=C(C=C4)NC(=O)C(C)N)C)O)O)NC
InChI Key: MRCNWCHLQHYMMZ-UHFFFAOYSA-N
Can. SMILES: CC(C(=O)NC1=CC=C(C=C1)C(=O)NC2=NC(=O)N(C=C2)C3CC(C(C(C)O3)OC4C(C(C(C(C)O4)NC)O)O)O)N
InChI: InChI=1S/C27H38N6O9/c1-12(28)24(37)30-16-7-5-15(6-8-16)25(38)31-18-9-10-33(27(39)32-18)19-11-17(34)23(14(3)40-19)42-26-22(36)21(35)20(29-4)13(2)41-26/h5-10,12-14,17,19-23,26,29,34-36H,11,28H2,1-4H3,(H,30,37)(H,31,32,38,39)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/3082738
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968/45/6/45_6_846/_article/-char/en

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