Compound ID | 3367

Sperabillin

Class: Membrane-active agent

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus (including strains resistant to methicillin, aminoglycosides, lincosamides, or macrolides), aminoglycoside-resistant and -susceptiblePseudomonas aeruginosa, Alcaligenes faecalis, and Acinetobacter calcoaceticus
Description: Natural product from Pseudomonas fluorescens; protected mice infected with Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, or Pseudomonas aeruginosa
Institute where first reported: Takeda Chemical Industries, Ltd.
Year first mentioned: 1992
Development status: Experimental
Chemical structure(s):
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Molecular weight: 398.33
Iso. SMILES: C/C=C\C=C\C(=O)NC[C@@H](C[C@H](CC(=O)NCCC(=N)N)N)O.Cl.Cl
InChI Key: OQKJNDABNFAQAJ-JDZFPWRWSA-N
Can. SMILES: C/C=C\C=C\C(=O)NC[C@@H](C[C@H](CC(=O)NCCC(=N)N)N)O.Cl.Cl
InChI: InChI=1S/C15H27N5O3.2ClH/c1-2-3-4-5-14(22)20-10-12(21)8-11(16)9-15(23)19-7-6-13(17)18;;/h2-5,11-12,21H,6-10,16H2,1H3,(H3,17,18)(H,19,23)(H,20,22);2*1H/b3-2-,5-4+;;/t11-,12-;;/m1../s1

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