Compound ID | 3373

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Cefuzonam

Class: Beta-lactam (cephalosporin, second generation)

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Neisseria gonorrhoeae, Haemophilus influenzae, Helicobacter pylori, and Propionibacterium acnes; cell wall synthesis inhibitor
Description: Semi-synthetic compound but generated by fully synthetic route; injectable
Year first mentioned: 1987
Development status: Experimental
Chemical structure(s):
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Molecular weight: 513.6
Iso. SMILES: CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)CSC4=CN=NS4)C(=O)O
InChI Key: CXHKZHZLDMQGFF-ZSDSSEDPSA-N
Can. SMILES: CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@@H]2C(=O)N3C(=C(CSC4=CN=NS4)CS[C@H]23)C(=O)O
InChI: InChI=1S/C16H15N7O5S4/c1-28-21-9(7-5-31-16(17)19-7)12(24)20-10-13(25)23-11(15(26)27)6(4-30-14(10)23)3-29-8-2-18-22-32-8/h2,5,10,14H,3-4H2,1H3,(H2,17,19)(H,20,24)(H,26,27)/b21-9-/t10-,14-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/6336505
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968b/47/8/47_1013/_article/-char/en

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