Compound ID | 3377

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Leucinostatin A3

Class: Antimicrobial peptide

Agent Type: Semisynthetic; Direct acting;
Spectrum of activity: Gram-positive
Mechanism of action: Membrane-active agent. Targets membrane phospholipid
Target Pathogen: Active against Staphylococcus aureus
Description: Semi-synthetic compound based on the natural product leucinostatin A from Paecilomyces marquandii
Year first mentioned: 1995
Development status: Experimental
External links:
Citations:
  • https://journals.asm.org/doi/10.1128/aac.9.6.893?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed
  • https://www.jstage.jst.go.jp/article/antibiotics1968/48/3/48_3_254/_article/-char/en

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