Compound ID | 3401
CC-11050
Synonym(s): Dovramilast | AMR-634 | AMR 634 | AMR634
Class: Immunomodulator agent
| Details of activity: | Active against Mycobacterium tuberculosis; targets host phosphodiesterase 4 (PDE4) to regulate inflammatory response |
| Description: | Synthetic compound; improves bacterial clearance and moderates infection induced inflammation with isoniazid in rabbits with TB |
| Institute where first reported: | Medicines Development for Global Health |
| Year first mentioned: | 2016 |
| Highest developmental phase: | Phase 2 (NCT03807362) |
| Development status: | Active |
| External links: | |
| Main Source: | https://doi.org/10.1016/j.ebiom.2016.01.015 |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us.
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.