Compound ID | 3402

Update compound information

SQ109

Synonym(s): SQ-109  |  SQ 109  |  MMV687273

Class: Ethylenediamine

Details of activity: Active against Mycobacterium tuberculosis; mycolate transporter (MmpL3) inhibitor
Description: Synthetic compound; contains 1,2 ethylenediamine (ethambutol) pharmacophore
Institute where first reported: Suquella Inc.
Year first mentioned: 2005
Highest developmental phase: Phase 2
Development status: Active
Chemical structure(s):
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Molecular weight: 330.55
Iso. SMILES: CC(=CCC/C(=C/CNCCNC1C2CC3CC(C2)CC1C3)/C)C
InChI Key: JFIBVDBTCDTBRH-REZTVBANSA-N
Can. SMILES: CC(=CCC/C(=C/CNCCNC1C2CC3CC(C2)CC1C3)/C)C
InChI: InChI=1S/C22H38N2/c1-16(2)5-4-6-17(3)7-8-23-9-10-24-22-20-12-18-11-19(14-20)15-21(22)13-18/h5,7,18-24H,4,6,8-15H2,1-3H3/b17-7+
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/5274428
Guide to Pharmacology: SQ-109
Citations:
  • https://www.nature.com/articles/s42003-022-03693-2
  • https://doi.org/10.2217/fmb.12.56
  • https://academic.oup.com/jac/article/56/5/968/893073

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