Compound ID | 3414
EB003
Synonym(s): EB-003 | EB 003
| Agent Type: | Indirect acting; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Targets strains containing Shiga toxin gene to form double stranded breaks leading to bacterial death |
| Target Pathogen: | Active against Escherichia coli |
| Description: | DNA encoding nuclease that targets Shiga-toxin (Stx) sequence; a microbiome modulating agent |
| Institute where first reported: | Eligo Bioscience |
| Year first mentioned: | 2021 |
| Highest development stage: | Preclinical |
| Development status: | Experimental |
| External links: | |
| Citations: |
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