Compound ID | 3425

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Korormicin

Class: Natural product antibiotic (lactone)

Spectrum of activity: Gram-negative
Details of activity: Active against marine Gram-negative bacteria; marine bacteria NADH-quinone reductase inhibitor
Description: Natural product from Pseudoalteromonas sp. F-420; only active against marine Gram-negatives??; mechanism of action see: https://www.jstage.jst.go.jp/article/antibiotics1968/52/2/52_2_182/_article/-char/en and https://www.jstage.jst.go.jp/article/bpb1993/22/10/22_10_1064/_article/-char/en
Year first mentioned: 1997
Development status: Experimental
Chemical structure(s):
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Molecular weight: 433.58
Iso. SMILES: CCCCCCCCC1C(O1)C/C=C/C=C\C(CC(=O)NC2=CC(OC2=O)(C)CC)O
InChI Key: OXOAWIMFJLEQMT-MBGGJNPXSA-N
Can. SMILES: CCCCCCCCC1C(C/C=C/C=C\C(CC(=O)NC2=CC(C)(CC)OC2=O)O)O1
InChI: InChI=1S/C25H39NO5/c1-4-6-7-8-9-12-15-21-22(30-21)16-13-10-11-14-19(27)17-23(28)26-20-18-25(3,5-2)31-24(20)29/h10-11,13-14,18-19,21-22,27H,4-9,12,15-17H2,1-3H3,(H,26,28)/b13-10+,14-11-
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/9845752
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/52/2/52_2_182/_article/-char/en
  • https://www.jstage.jst.go.jp/article/antibiotics1968/50/11/50_11_949/_article/-char/en

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