Compound ID | 345

RWJ-442831

Class: Beta-lactam

Agent Type: Semisynthetic; Direct acting;
Spectrum of activity: Gram-positive
Mechanism of action: Cell wall synthesis inhibitor
Combined with other compounds: Could be combined with aztreonam, fosfomycin, gentamicin or levofloxacin for empiric therapy
Institute where first reported: Microcide Pharmaceuticals; Essential Therapeutics, USA (Ceased); Johnson & Johnson Pharmaceutical
Year first mentioned: 2000
Development status: Experimental
Reason dropped: The collaboration between Johnson and Johnson Pharma and Essential Therapeutics which seems to have stopped with the closure of Essential Therapeutics

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