Compound ID | 3463
D-9-mer peptides (diastereomer)
Class: Antimicrobial peptide
| Agent Type: | Semisynthetic; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Membrane-active agent |
| Target Pathogen: | Active against methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa |
| Description: | Semi-synthetic peptides derived from defensins; shows synergistic effect with piperacillin, ceftazidime, tetracycline, chloramphenicol, and rifampicin |
| Year first mentioned: | 2007 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.jstage.jst.go.jp/article/jibs/76/1/76_1_1_25/_article/-char/en |
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