Compound ID | 3475

Update compound information

E-4480, E4480, E 4480

Synonym(s): E4480  |  E 4480

Class: Fluoroquinolone

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus, Streptococcus pneumoniae, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Pseudomonas aeruginosa, and Clostridium sp.;
Description: Synthetic compound; monofluorinated; superior to ciprofloxacin in protecting mice against systemic infection caused by Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa
Year first mentioned: 1990
Development status: Experimental
Chemical structure(s):
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Molecular weight: 331.34
Iso. SMILES: CC1(N)CN(C1)c1cc2n(cc(C(=O)O)c(=O)c2cc1F)C1CC1
InChI Key: UAYYWDWWESZIPA-UHFFFAOYSA-N
Can. SMILES: CC1(CN(C1)C2=CC3=C(C=C2F)C(=O)C(=CN3C4CC4)C(=O)O)N
InChI: InChI=1S/C17H18FN3O3/c1-17(19)7-20(8-17)14-5-13-10(4-12(14)18)15(22)11(16(23)24)6-21(13)9-2-3-9/h4-6,9H,2-3,7-8,19H2,1H3,(H,23,24)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/substance/274051591
Citation: https://journals.asm.org/doi/10.1128/aac.34.12.2318

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