Compound ID | 3497
MBX-4888A
Synonym(s): Lee-1810 | 4888A
Class: Aminoglycoside
| Agent Type: | Semisynthetic; Direct acting; |
| Spectrum of activity: | Antimycobacterial |
| Mechanism of action: | Protein synthesis inhibitor |
| Target Pathogen: | Active against Mycobacterium tuberculosis |
| Description: | Semi-synthetic compound; spectinamide; not susceptible to efflux by Mycobacterium tuberculosis efflux pumps; shows favourable physiochemical properties due to good distribution and retention times in tissues |
| Year first mentioned: | 2016 |
| Highest development stage: | Preclinical |
| Development status: | Experimental |
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