Compound ID | 3501

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Merafloxacin

Synonym(s): CI-934

Class: Fluoroquinolone

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: DNA synthesis inhibitor
Target Pathogen: Active against Staphylococcus aureus, Streptococcus pneumoniae, Enterococcus sp., Streptococci sp., Enterobacter sp., Escherichia coli, Klebsiella sp., Salmonella sp., Shigella sp., and anaerobic cocci
Year first mentioned: 1984
Development status: Experimental
Chemical structure(s):
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Molecular weight: 379.4
Iso. SMILES: CCNCC1CCN(C1)C2=C(C=C3C(=C2F)N(C=C(C3=O)C(=O)O)CC)F
InChI Key: BAYYCLWCHFVRLV-UHFFFAOYSA-N
Can. SMILES: CCNCC1CCN(C1)C2=C(C3=C(C=C2F)C(=O)C(=CN3CC)C(=O)O)F
InChI: InChI=1S/C19H23F2N3O3/c1-3-22-8-11-5-6-24(9-11)17-14(20)7-12-16(15(17)21)23(4-2)10-13(18(12)25)19(26)27/h7,10-11,22H,3-6,8-9H2,1-2H3,(H,26,27)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/121833
Citations:
  • https://journals.asm.org/doi/10.1128/aac.29.5.852
  • https://journals.asm.org/doi/10.1128/aac.28.6.766?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed

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