Compound ID | 3507

Update compound information

A20L 

Class: Antimicrobial peptide

Spectrum of activity: Gram-negative
Details of activity: Active against Klebsiella pneumoniae; membrane-active agent (increases permeability of outer membrane)
Description: Synthetic compound; designed from antimicrobial peptide V12KL; shows haemolytic activity at 2-7x MIC; shows no cytotoxicity to RAW264.7 cells (up to 128 mg/L, highest concentration tested)
Year first mentioned: 2015
Development status: Experimental
External links:
Citations:
  • https://link.springer.com/article/10.1186/s12896-015-0189-x?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=asm
  • https://journals.asm.org/doi/10.1128/spectrum.03979-23

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