Compound ID | 3512

Update compound information

D66 

Class: Membrane-active agent

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Membrane-active agent
Target Pathogen: Active against Staphylococcus aureus and Salmonella enterica serotype Typhimurium
Description: Synthetic compound from screening, Maybridge HitFinderTM v11, a library of compounds with drug-like properties
Year first mentioned: 2022
Development status: Experimental
Chemical structure(s):
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Molecular weight: 378.3
Iso. SMILES: C1CN(CCN(C1)C(=O)NC2=CC(=CC(=C2)Cl)Cl)CC3=CC=CC=C3
InChI Key: CWSDZVKPMONNSH-UHFFFAOYSA-N
Can. SMILES: C1=CC=C(C=C1)CN2CCCN(CC2)C(=O)NC3=CC(=CC(=C3)Cl)Cl
InChI: InChI=1S/C19H21Cl2N3O/c20-16-11-17(21)13-18(12-16)22-19(25)24-8-4-7-23(9-10-24)14-15-5-2-1-3-6-15/h1-3,5-6,11-13H,4,7-10,14H2,(H,22,25)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/2795983
Citations:
  • https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010606
  • https://journals.asm.org/doi/10.1128/msphere.00772-23

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