Compound ID | 3514
Synonym(s): Initiation factor 1-derived peptide from C. difficile | IF1-derived peptide
Class: Antimicrobial peptide
Spectrum of activity: | Gram-positive |
Details of activity: | Active against Clostridioides difficile; protein synthesis inhibitor (designed to mimic initiation factor 1) and additionally a membrane-active agent |
Description: | Synthetic compound; peptide designed from Clostridium difficile initiation factor 1; short alpha-helix structure |
Year first mentioned: | 2024 |
Development status: | Experimental |
External links: | |
Citation: | https://journals.asm.org/doi/10.1128/spectrum.02773-23 |