Compound ID | 3517
1D10
Class: Bacteriophage and/or bacteriophage-derived product
| Agent Type: | Direct acting; Bacteriophage or bacteriphage-derived product; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Cell wall active agent (i.e. partial degradation of the peptidoglycan) and membrane-active agent |
| Target Pathogen: | Active against Acinetobacter baumannii (without addition of EDTA to act as sensitizer) |
| Description: | Synthetic bacteriophage lysin; engineered lysin containing a outer-membrane permeabilizing peptide from cecropin A , the cell wall binding domain of bacteriophage ϕKZ, a linker, and an enzymatically active domain of the virion-associated lysin of phage BcepC6B |
| Year first mentioned: | 1999 |
| Development status: | Experimental |
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