Compound ID | 3518
Turnercyclamycin
Class: Lipopeptide
| Agent Type: | Natural product; Direct acting; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Membrane-active agent |
| Target Pathogen: | Active against Escherichia coli including strains harbouring MCR-1, Klebsiella pneumoniae, and Acinetobacter baumannii |
| Description: | Natural product from Teredinibacter turnerae (a shipworm symbiont); shows no haemolytic activity and cytotoxicity at 64 ug/ml (highest concentration tested vs MIC 1-8 ug/ml) |
| Year first mentioned: | 2021 |
| Development status: | Experimental |
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