Compound ID | 3521

Update compound information

Bilothiazole F

Class: Natural product antibiotic (thiazole)

Spectrum of activity: Gram-positive
Details of activity: Studies on mode of action suggest this compound is cell wall synthesis inhibitor
Description: Natural product from an identified biosynthetic gene cluster belonging to the human microbiome isolate Bilophila strain; induced beta-lactam whole-cell biosensor
Year first mentioned: 2025
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 307.35
Iso. SMILES: OC1=C(C2=NC(C3=N[C@@](C(O)=O)([H])CS3)=CS2)N=CC([H])=C1[H]
InChI Key: NSEPTDCAKOWGCI-ZETCQYMHSA-N
Can. SMILES: C1([H])=CN=C(C(=C1[H])O)C2=NC(=CS2)C3=N[C@@]([H])(CS3)C(=O)O
InChI: InChI=1S/C12H9N3O3S2/c16-8-2-1-3-13-9(8)11-14-6(4-20-11)10-15-7(5-19-10)12(17)18/h1-4,7,16H,5H2,(H,17,18)/t7-/m0/s1
External links:
Citation: https://pubs.acs.org/doi/10.1021/acssynbio.5c00042

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.