Compound ID | 3538

Update compound information

WFQ-228

Class: Fluoroquinolone

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-negative
Mechanism of action: DNA synthesis inhibitor
Target Pathogen: Active against quinolone-resistant and -susceptible Escherichia coli and Pseudomonas aeruginosa, quinolone-resistant Acinetobacter baumannii
Institute where first reported: Wakunaga Pharmaceutical Co., Ltd.
Year first mentioned: 2018
Development status: Experimental
Chemical structure(s):
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Molecular weight: 478.88
Iso. SMILES: CC1=C2C(=C(C(=C1F)N3CC(C3)NC)Cl)N(C=C(C2=O)C(=O)O)C4=CC(=C(C=C4CO)F)N
InChI Key: BUYCHMJCHCPDRG-UHFFFAOYSA-N
Can. SMILES: CC1=C(C(=C(C2=C1C(=O)C(=CN2C3=C(C=C(C(=C3)N)F)CO)C(=O)O)Cl)N4CC(C4)NC)F
InChI: InChI=1S/C22H21ClF2N4O4/c1-9-16-19(17(23)20(18(9)25)28-5-11(6-28)27-2)29(7-12(21(16)31)22(32)33)15-4-14(26)13(24)3-10(15)8-30/h3-4,7,11,27,30H,5-6,8,26H2,1-2H3,(H,32,33)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/132243266
Citation: https://www.jstage.jst.go.jp/article/cpb/66/3/66_c17-00717/_article/-char/en

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