Compound ID | 3568

Update compound information

GmPcide PS757 

Class: Small molecule antibacterial agent

Agent Type: Synthetic; Direct acting;
Spectrum of activity: Gram-positive
Mechanism of action: Membrane-active agent
Target Pathogen: Active against Streptococcus pyogenes
Description: Synthetic compound; contains peptidomimetic dihydrothiazolo ring-fused 2-pyridone scaffold; prevents/eradicates initiation, formation, maturation, and fully formed Streptococcus pyogenes biofilm
Year first mentioned: 2022
Development status: Experimental
External links:
Citations:
  • https://www.pnas.org/doi/abs/10.1073/pnas.2210912119?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed
  • https://www.science.org/doi/10.1126/sciadv.adn7979

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