Compound ID | 3575
Synonym(s): SPR-113 | SPR 113
Details of activity: | Active against multidrug-resistant and extensively-resistant Mycobacterium tuberculosis |
Description: | Shows efficacy in treating Mycobacterium tuberculosis infection in human macrophages and murine model; shows no activity against cytochrome P-450 and hERG (high selectivity) |
Institute where first reported: | Sphaera Pharma and the Drug Discovery Research Centre (DDRC) of the Translational Health Science and Technology Institute, India |
Highest developmental phase: | Preclinical |
Development status: | Experimental |