Compound ID | 3578

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Capistruin

Class: Antimicrobial peptide

Agent Type: Natural product; Direct acting;
Spectrum of activity: Gram-negative
Mechanism of action: RNA synthesis inhibitor. RNA polymerase inhibitor (RNAP inhibitor)
Target Pathogen: Active against Burkholderia strains, Pseudomonas aeruginosa, and Escherichia coli
Description: Natural product from Burkholderia thailandensis E264; a lasso peptide
Year first mentioned: 2008
Development status: Experimental
External links:
Citations:
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC3143284/
  • https://pubs.acs.org/doi/10.1021/ja802966g

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