Compound ID | 3580
CLB073
Synonym(s): CLB 073 | CLB-073
Class: Small molecule antibacterial agent
| Agent Type: | Synthetic; Direct acting; |
| Spectrum of activity: | Antimycobacterial |
| Mechanism of action: | Targets the enzyme adenylyl cyclase (Rv1625c) to block ability of Mycobacterium tuberculosis to metabolise cholesterol |
| Target Pathogen: | Active against Mycobacterium tuberculosis |
| Description: | Synthetic compound; enhances efficacy of Nix-TB drug regimen |
| Institute where first reported: | Calibr (US) |
| Year first mentioned: | 2023 |
| Highest developmental phase: | Preclinical |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.newtbdrugs.org/pipeline/compound/clb073 |
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