Compound ID | 3580
Synonym(s): CLB 073 | CLB-073
Details of activity: | Active against Mycobacterium tuberculosis; targets the enzyme adenylyl cyclase (Rv1625c) to block ability of Mycobacterium tuberculosis to metabolise cholesterol |
Description: | Synthetic compound; enhances efficacy of Nix-TB drug regimen |
Institute where first reported: | CalibrĀ (US) |
Year first mentioned: | 2023 |
Highest developmental phase: | Preclinical |
Development status: | Experimental |
External links: | |
Citation: | https://www.newtbdrugs.org/pipeline/compound/clb073 |