Compound ID | 3585

Update compound information

Compound 42

Class: Small molecule antibacterial agent

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-negative
Mechanism of action: Flavodoxin inhibitor
Target Pathogen: Active against Helicobacter pylori
Description: Synthetic compound; shows a therapeutic index of 37.7 (MIC at 0.53 uM vs HeLa cells cytotoxicity at 20 uM)
Year first mentioned: 2013
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 219.57
Iso. SMILES: C1=C(C=C(C(=C1F)/C=C/[N+](=O)[O-])F)Cl
InChI Key: UGPXGKZHLDUHMI-OWOJBTEDSA-N
Can. SMILES: C(=C\[N+](=O)[O-])/C1=C(C=C(C=C1F)Cl)F
InChI: InChI=1S/C8H4ClF2NO2/c9-5-3-7(10)6(8(11)4-5)1-2-12(13)14/h1-4H/b2-1+
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/71818107
Citation: https://pubs.acs.org/doi/10.1021/jm400786q

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.