Compound ID | 3585

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Compound 42

Class: Small molecule antibacterial agent

Spectrum of activity: Gram-negative
Details of activity: Active against Helicobacter pylori; flavodoxin inhibitor
Description: Synthetic compound; shows a therapeutic index of 37.7 (MIC at 0.53 uM vs HeLa cells cytotoxicity at 20 uM)
Year first mentioned: 2013
Development status: Experimental
Chemical structure(s):
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Molecular weight: 219.57
Iso. SMILES: C1=C(C=C(C(=C1F)/C=C/[N+](=O)[O-])F)Cl
InChI Key: UGPXGKZHLDUHMI-OWOJBTEDSA-N
Can. SMILES: C(=C\[N+](=O)[O-])/C1=C(C=C(C=C1F)Cl)F
InChI: InChI=1S/C8H4ClF2NO2/c9-5-3-7(10)6(8(11)4-5)1-2-12(13)14/h1-4H/b2-1+
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/71818107
Citation: https://pubs.acs.org/doi/10.1021/jm400786q

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