Compound ID | 3598

Update compound information

UK-38,006

Synonym(s): 6-Beta-Iodopenicillanic acid  |  UK 38,006  |  UK38006

Class: Beta-lactamase inhibitor

Spectrum of activity: Gram-positive
Details of activity: Active against beta-lactamase producing methicillin-resistant Staphylococcus aureus and Neisseria gonorrhoeae
Combined with other compounds: Yes
Description: Synthetic compound; shows no intrinsic antibacterial activity; potentiates beta-lactams (shows synergistic effect with piperacillin and mezlocillin)
Institute where first reported: Pfizer Central Research, Sandwich, Kent, England
Year first mentioned: 1981
Development status: Experimental
Chemical structure(s):
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Molecular weight: 327.14
Iso. SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)I)C(=O)O)C
InChI Key: XWDSFLSFDJZQTM-ALEPSDHESA-N
Can. SMILES: CC1(C)[C@H](C(=O)O)N2C(=O)[C@H]([C@H]2S1)I
InChI: InChI=1S/C8H10INO3S/c1-8(2)4(7(12)13)10-5(11)3(9)6(10)14-8/h3-4,6H,1-2H3,(H,12,13)/t3-,4+,6-/m1/s1
External links:
Structure link: https://pubchem.ncbi.nlm.nih.gov/compound/121940
Citation: https://journals.asm.org/doi/10.1128/aac.20.3.327

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