Compound ID | 3609

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ICI 194008

Synonym(s): ICI-194008  |  ICI194008

Class: Beta-lactam

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Streptococcus sp., Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, and Enterobacter aerogenes (similar activity profile to ceftazidime); cell wall synthesis inhibitor
Description: Semisynthetic compound derived from cephalosporin
Year first mentioned: 1987
Development status: Experimental
Chemical structure(s):
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Molecular weight: 660.75
Iso. SMILES: CCN(CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N/OC(C)(C)C(=O)O)/C3=CSC(=N3)N)SC1)C(=O)[O-])C4=C5C=CSC5=[N+](C=N4)C
InChI Key: UTIIUUIQHFQQRL-SEVZJSAHSA-N
Can. SMILES: CCN(CC1=C(C(=O)[O-])N2C(=O)[C@H]([C@H]2SC1)NC(=O)/C(=N/OC(C)(C)C(=O)O)/C3=CSC(=N3)N)C4=NC=[N+](C)C5=C4C=CS5
InChI: InChI=1S/C26H28N8O7S3/c1-5-33(18-13-6-7-42-21(13)32(4)11-28-18)8-12-9-43-22-16(20(36)34(22)17(12)23(37)38)30-19(35)15(14-10-44-25(27)29-14)31-41-26(2,3)24(39)40/h6-7,10-11,16,22H,5,8-9H2,1-4H3,(H4-,27,29,30,35,37,38,39,40)/b31-15+/t16-,22-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/9578286
Citation: https://journals.asm.org/doi/10.1128/aac.31.12.1997

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