Compound ID | 3619

Update compound information

ME1071

Synonym(s): ME-1071  |  ME 1071

Class: Beta-lactamase inhibitor (MBL inhibitor)

Spectrum of activity: Gram-negative
Details of activity: Active against metallo-β-lactamase producing strains of Pseudomonas aeruginosa
Combined with other compounds: Yes
Description: Synthetic compound; maleic acid derivative; potentiates carbapenem and ceftazidime; no intrinsic antibacterial activity
Institute where first reported: Meiji Seika Kaisha Ltd. (Tokyo, Japan)
Year first mentioned: 2010
Development status: Experimental
Chemical structure(s):
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Molecular weight: 216.14
Iso. SMILES: CC/C(=C(\CC)/C(=O)[O-])/C(=O)[O-].[Na+].[Na+]
InChI Key: GLJFFZOATODZQQ-XNOMRPDFSA-L
Can. SMILES: CC/C(=C(\CC)/C(=O)[O-])/C(=O)[O-].[Na+].[Na+]
InChI: InChI=1S/C8H12O4.2Na/c1-3-5(7(9)10)6(4-2)8(11)12;;/h3-4H2,1-2H3,(H,9,10)(H,11,12);;/q;2*+1/p-2/b6-5-;;
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/16064853
Citation: https://journals.asm.org/doi/10.1128/aac.01397-09

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