Compound ID | 3622

Update compound information

Piperazinylsulfonylaryl compound

Synonym(s): 4-Amino-1-[4-[4-[6-chloro-4-[difluoro(phenyl)methyl]-2-pyridyl]piperazin-1-yl]sulfonylphenyl]pyrrolidin-2-one

Class: Small molecule antibacterial agent

Spectrum of activity: Gram-negative
Description: Synthetic compound; analogues reported
Institute where first reported: Hoffman-La Roche Inc.
Year first mentioned: 2021
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 562.03
Iso. SMILES: NC1CN(C(=O)C1)c2ccc(cc2)S(=O)(=O)N3CCN(CC3)c4cc(cc(Cl)n4)C(F)(F)c5ccccc5
InChI Key: DKBZGINOWOEUGT-UHFFFAOYSA-N
Can. SMILES: C1=CC=C(C=C1)C(C2=CC(=NC(=C2)Cl)N3CCN(CC3)S(=O)(=O)C4=CC=C(C=C4)N5CC(CC5=O)N)(F)F
InChI: InChI=1S/C26H26ClF2N5O3S/c27-23-14-19(26(28,29)18-4-2-1-3-5-18)15-24(31-23)32-10-12-33(13-11-32)38(36,37)22-8-6-21(7-9-22)34-17-20(30)16-25(34)35/h1-9,14-15,20H,10-13,16-17,30H2
External links:
Structure link: https://pubchem.ncbi.nlm.nih.gov/compound/168238514
Citation: https://patents.google.com/patent/WO2023072794A1/en
Patent: WO2023072794

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.