Compound ID | 3636

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Pyridopyrimidine compound 14d

Synonym(s): Compound 14d

Class: Small molecule antibacterial agent

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-negative
Mechanism of action: Fatty acid synthesis inhibitor. Biotin carboxylase inhibitor/ AccC inhibitor/ Acetyl-CoA carboxylase inhibitor
Target Pathogen: Active against Escherichia coli
Description: Synthetic compound
Institute where first reported: Achaogen
Year first mentioned: 2019
Development status: Experimental
Chemical structure(s):
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Molecular weight:
Iso. SMILES: CC1=NC=C(S1)C2=C(C(=CC=C2)Cl)C3=C(N=C4C(=C3)C=NC(=N4)N)N5C[C@@H]6[C@H](C5)C6N
InChI Key: CINSALQQASTTDE-RTHVDDQRSA-N
Can. SMILES: CC1=NC=C(C2=C(C3=C(N=C4C(=C3)C=NC(=N4)N)N5C[C@H]6[C@@H](C5)C6N)C(=CC=C2)Cl)S1
InChI: InChI=1S/C22H20ClN7S/c1-10-26-7-17(31-10)12-3-2-4-16(23)18(12)13-5-11-6-27-22(25)29-20(11)28-21(13)30-8-14-15(9-30)19(14)24/h2-7,14-15,19H,8-9,24H2,1H3,(H2,25,27,28,29)/t14-,15+,19?
External links:
Structure link: https://pubchem.ncbi.nlm.nih.gov/compound/155538218
Citation: https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b00625
Patent: WO2018023081

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