Compound ID | 3651

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Dipeptide mimetic 7

Synonym(s): (S)-2-Amino-N-(4-ethynylphenyl)-3-(1H-indol-3-yl) propanamide

Class: Antimicrobial peptide

Agent Type: Synthetic; Antibiofilm;
Spectrum of activity: Gram-positive
Mechanism of action: Membrane-active agent
Target Pathogen: Active against Staphylococcus aureus
Description: Synthetic compound; peptide mimetic; shows high selectivity index; eradicates established biofilms and prevents biofilm formation
Institute where first reported: Harbin Engineering University, China
Year first mentioned: 2022
Development status: Experimental
Chemical structure(s):
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Molecular weight:
Iso. SMILES: C(#C)C1C=CC(NC(C(N)C(C)C)=O)=CC=1
InChI Key: PSZNBPXUGJIZCG-UHFFFAOYSA-N
Can. SMILES: C#CC1=CC=C(C=C1)NC(=O)C(C(C)C)N
InChI: InChI=1S/C13H16N2O/c1-4-10-5-7-11(8-6-10)15-13(16)12(14)9(2)3/h1,5-9,12H,14H2,2-3H3,(H,15,16)
External links:
Citation: https://www.sciencedirect.com/science/article/abs/pii/S0223523421008266?via%3Dihub

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