Compound ID | 3661

Update compound information

REDX07638

Synonym(s): REDX 07638  |  REDX-07638

Class: DNA synthesis inhibitor

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: DNA synthesis inhibitor. DNA gyrase inhibitor and topoisomerase IV inhibitor
Target Pathogen: Active against Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, and Acinetobacter baumannii
Description: A novel bacterial topoisomerase inhibitor with tricyclic northern head group
Institute where first reported: Redx Pharma, Alderley Park, Cheshire, United Kingdom
Year first mentioned: 2016
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight:
Iso. SMILES: O=C1N(CCN2CCC(NCC3=NC=4NC(COC4C=C3F)=O)CC2)C5=CC(OC)=CC=C5C6=CON=C16
InChI Key: BGOBZNLUFHCGIX-UHFFFAOYSA-N
Can. SMILES: COC1=CC2=C(C=C1)C3=CON=C3C(=O)N2CCN4CCC(CC4)NCC5=C(C=C6C(=N5)NC(=O)CO6)F
InChI: InChI=1S/C26H27FN6O5/c1-36-16-2-3-17-18-13-38-31-24(18)26(35)33(21(17)10-16)9-8-32-6-4-15(5-7-32)28-12-20-19(27)11-22-25(29-20)30-23(34)14-37-22/h2-3,10-11,13,15,28H,4-9,12,14H2,1H3,(H,29,30,34)
External links:
Citation: https://doi.org/10.1128/AAC.02100-16

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.