Compound ID | 377
SKF 104662
Class: Glycopeptide
| Spectrum of activity: | Gram-negative |
| Details of activity: | Activity against Clostridium difficile |
| Institute where first reported: | SmithKline Beecham; GSK |
| Year first mentioned: | 1988 |
| Highest developmental phase: | Phase 1 |
| Development status: | Inactive |
| Reason Dropped: | Activity very similar to vancomycin and teicoplanin, very little is known about this. Either unpublished data or wasn't promising in terms of passing non-inferior tests or superiority. From ICAAC, 1984, 1988, animal trials in mice showed reduced toxic potential compared to vancomycin. |
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