Compound ID | 39
NAI-603
Synonym(s): VIC 200603 | VIC 603
Class: Glycolipodepsipeptide
| Spectrum of activity: | Gram-positive |
| Details of activity: | MRSA (methicillin resistant Staphylococcus aureus) and VRE (vancomycin resistant Enterococcus sp.); ramoplanin derivative, well tolerated in mouse models. In mouse septicaemia models infected with MRSA, it was more effective than vancomycin and teicoplanin. It is also effective against Enterococcus faecalis |
| Propensity to select resistant mutants: | Yes |
| Institute where first reported: | NAICONS, Milan, Italy |
| Year first mentioned: | 2014 |
| Highest developmental phase: | Preclinical |
| Development status: | Experimental |
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