Compound ID | 396
HKI 9924109
Class: Beta-lactam (siderophore acylaminopenicillin)
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Cell wall inhibitor; tested against 44 NFGNB of which near a quarter of these were not inhibited by HKI 9924109, HKI 9924154 and HKI 9924155. These compounds were also found to inhibit certain species of the Enterobacteriaceae family. |
| Description: | Shapiro S, Thenoz L, Heinisch L, et al. Activities of novel siderophoric beta-lactams towards Gram-negative bacteria. 45th-Intersci-Conf-Antimicrob-Agents-Chemother 2005;200 |
| Institute where first reported: | Basilea Pharmaceutica AG, Switzerland; Hans Knöll Institute for Natural Products Research, Germany |
| Year first mentioned: | 2001 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| External links: | |
| Citation: |
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