Compound ID | 397
HKI 9924154
Class: Beta-lactam
| Agent Type: | Semisynthetic; Small molecule; Direct acting; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Cell wall synthesis inhibitor |
| Target Pathogen: | Active against Enterobacteriaceae |
| Description: | Ampicillin-type with siderophore conjugate; Shapiro S, Thenoz L, Heinisch L, et al. Activities of novel siderophoric beta-lactams towards Gram-negative bacteria. 45th-Intersci-Conf-Antimicrob-Agents-Chemother 2005;201 |
| Institute where first reported: | Basilea Pharmaceutica AG, Switzerland; Hans Knöll Institute for Natural Products Research, Germany |
| Year first mentioned: | 2001 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://pubs.acs.org/doi/10.1021/jm010546b |
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