Compound ID | 404
Mureidomycin C
Class: Antimicrobial peptide
| Agent Type: | Natural product; Direct acting; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Cell wall synthesis inhibitor. MraY inhibitor; interferes with cell-wall synthesis by inhibiting transfer of the peptidoglycan precursor moiety (MurNAc-pentapeptide) to the membrane lipid carrier, undecaprenyl phosphate |
| Description: | Natural product from Streptomyces flavidovirens; a peptidylnucleoside (uridyl) peptide |
| Institute where first reported: | Sankyo Co. Ltd, Japan |
| Year first mentioned: | 1991 |
| Development status: | Experimental |
| Reason dropped: | Rapid resistance due to transport loss |
| External links: | |
| PubChem link: | https://pubchem.ncbi.nlm.nih.gov/compound/101627954 |
| Guide to Pharmacology: | mureidomycin C |
| Citations: |
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