Compound ID | 404
Mureidomycin C
Class: MraY inhibitor
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Interferes with cell-wall synthesis by inhibiting transfer of the peptidoglycan precursor moiety (MurNAc-pentapeptide) to the membrane lipid carrier, undecaprenyl phosphate. |
| Description: | Uridyl peptide |
| Institute where first reported: | Sankyo Co. Ltd, Japan |
| Year first mentioned: | 1991 |
| Development status: | Inactive |
| Reason Dropped: | Rapid resistance due to transport loss (LS) |
| Chemical structure(s): |
| External links: | |
| Structure link: | https://pubchem.ncbi.nlm.nih.gov/compound/101627954 |
| Guide to Pharmacology: | mureidomycin C |
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